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AI can predict a protein's shape in minutes. That is not the same as knowing what it does

Biotechnology

AI can predict a protein's shape in minutes. That is not the same as knowing what it does

28 Aug 2026 · 9 min read

A fifty-year-old problem in biology broke open in 2020, and the method that cracked it does not simulate physics at all. Here is what a structure prediction is actually inferring, what its confidence score means, and the four things it still gets wrong.

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