Biotechnology
CRISPR as usually described breaks DNA and hopes the cell repairs it well. The editors reaching patients do not cut at all
21 Sept 2026 · 8 min read
Cutting both strands of DNA is excellent for switching a gene off and close to useless for correcting a single wrong letter — which is what most genetic disease actually is. Base and prime editors solve a different problem, chemically, without a break.
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